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New trial
Brain and CNS tumors

Phase I Trial of Anti-GARP CAR-T in Recurrent High-Grade Glioma

Trial ID
NCT06964737 on ClinicalTrials.gov
Cancer type
Glioma / Glioblastoma
Published in
New in Oncology - May 21, 2025

Ohio State is evaluating the safety, optimal dosing, and initial efficacy of anti-GARP CAR-T cell therapy in patients with recurrent grade III/IV gliomas through a treatment protocol that includes apheresis, surgery with CSF reservoir placement, and serial intracavitary infusions.

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