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Multiple solid tumors

Pilot Phase RFA/BA+RT for metastatic spine lesions: Radiofrequency ablation & radiotherapy

Trial ID
NCT07090122 on ClinicalTrials.gov
Cancer type
Solid Tumor
Stage of research
Exploratory
Published in
New in Oncology - Aug 15, 2025 (DOUBLE ISSUE)

This pilot randomized controlled study evaluates RFA with bone augmentation plus radiotherapy versus radiotherapy alone in patients with metastatic spine lesions from solid tumors (T5-L5). RFA employs radiofrequency-generated heat to ablate tumor tissue followed by bone augmentation for structural reinforcement, while radiotherapy uses high-energy radiation to target cancer cells. Conducted at the University of Minnesota, the trial aims to assess skeletal-related events and guide potential future treatment strategies.

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