New trial
Phase Ib Trial: Epcoritamab CD20/CD3 bispecific antibody for CNS lymphoma
- Trial ID
- NCT07082868 on ClinicalTrials.gov
- Cancer type
- CNS Lymphoma
- Stage of research
- Exploratory
- Location
- 8 Locations
- Published in
- New in Oncology - Aug 15, 2025 (DOUBLE ISSUE)
This trial at Memorial Sloan Kettering evaluates the safety of epcoritamab, CD20/CD3 bispecific antibody, in combination with ibrutinib, a BTK inhibitor, in patients with relapsed/refractory primary or secondary central nervous system lymphoma. The study uses dose escalation followed by expansion cohorts to establish tolerability and optimal dosing for further clinical development.
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