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Lymphoma

Phase I N-803 study of IL-15 agonist fusion protein in post-CAR T therapy

Trial ID
NCT07049432 on ClinicalTrials.gov
Cancer type
Lymphoma
Stage of research
Exploratory
Published in
New in Oncology - July 25, 2025

This Phase I trial seeks to determine the safety and tolerability of N-803, an IL-15 agonist fusion protein, administered as maintenance therapy following CD19-targeted CAR T-cell treatment for patients with relapsed or refractory B-cell non-Hodgkin lymphoma. Conducted by the University of Utah in Salt Lake City, the study explores whether N-803 can sustain responses and improve immune recovery post-CAR T therapy.

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