New trial
Phase 1b [225Ac]Ac-AKY-1189 Nectin-4 Radiopharmaceutical, a Nectin-4-directed alpha emitter.
- Trial ID
- NCT07020117 on ClinicalTrials.gov
- Cancer type
- Other Solid Tumors
- Stage of research
- First-in-human
- Published in
- New in Oncology - July 3, 2025
This first-in-human, two-part study led by Aktis Oncology evaluates the safety and maximum tolerated dose of [225Ac]Ac-AKY-1189 monotherapy in patients with advanced or metastatic solid tumors. Conducted at Grand Rapids, the trial explores a novel radioimmunotherapy for previously treated disease.
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