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Lymphoma

Phase I alectinib (ALK kinase inhibitor) plus duvelisib (PI3K delta-gamma inhibitor) dual-target trial

Trial ID
NCT07001384 on ClinicalTrials.gov
Cancer type
Anaplastic Large Cell Lymphoma
Stage of research
Exploratory
Location
7 Locations
Published in
New in Oncology - July 3, 2025

This study evaluates the safety and efficacy of alectinib lead-in followed by duvelisib combination to establish tolerable doses in relapsed/refractory ALK+ anaplastic large cell lymphoma. Conducted by Memorial Sloan Kettering and New York sites, it explores dose escalation and treatment durability in a second-line plus setting.

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