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Kidney cancer

Phase II Study of Ivonescimab in Advanced Clear Cell RCC

Trial ID
NCT06940518 on ClinicalTrials.gov
Cancer type
Kidney (Renal Cell) Carcinoma
Published in
New in Oncology - May 7, 2025

M.D. Anderson Cancer Center in Houston is evaluating ivonescimab—a PD-1 and VEGF bispecific antibody—administered IV every three weeks in patients with advanced clear cell RCC who have progressed on prior VEGF-targeted treatments. This trial aims to determine whether ivonescimab can effectively control disease in this heavily pretreated population.

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