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Multiple solid tumors

Phase 1a/1b Trial of BBO-11818 in Advanced KRAS Mutant Cancers

Trial ID
NCT06917079 on ClinicalTrials.gov
Cancer type
Solid Tumors
Published in
New in Oncology - May 7, 2025

BridgeBio Oncology is conducting a first-in-human study to assess the safety, pharmacokinetics, and preliminary antitumor activity of BBO-11818—a pan-KRAS inhibitor—in advanced, unresectable, or metastatic KRAS mutant solid tumors, either as monotherapy or in combination with agents like pembrolizumab, chemotherapy, or cetuximab.

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