New trial
Phase 1b glofitamab CD20/CD3 bispecific mAb for frontline DLBCL in older adults
- Trial ID
- NCT06765317 on ClinicalTrials.gov
- Cancer type
- Diffuse Large B-Cell Lymphoma
- Stage of research
- Exploratory
- Location
- 7 Locations
- Published in
- New in Oncology - July 3, 2025
This study evaluates a combination treatment using glofitamab with polatuzumab, obinutuzumab, and R-miniCHP for untreated patients (65+) with DLBCL, HGBCL, or transformed lymphoma. A response-adapted design based on interim PET scans supports tailored therapy in an investigational trial sponsored by Memorial Sloan Kettering Cancer Center.
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