What does a cancer clinical trial matching service do?

A matching service compares the details of your situation—such as diagnosis, stage, prior treatments, biomarkers, and location—with study criteria and scientific context. Sagely then prioritizes a small set of findings and explains why each may be worth discussing. The trial team makes the final eligibility decision.

Is this only about clinical trials?

No. Trial matching can point toward diagnostics, doctors involved in relevant studies, cancer centers with useful expertise, and other treatment questions worth discussing.

How does Sagely help me connect with a trial or expert?

When Sagely identifies a relevant study or expert, your guidance can include official study links and contacts, doctors involved in the work, and cancer centers to reach out to. You decide which options to explore. The trial team reviews your records and makes the final eligibility and enrollment decision.

What information do I need?

Start with what you know. Sage asks guided questions, and you can upload records you already have. Your diagnosis, stage, prior treatments, biomarkers, and test results can all help make the guidance more useful.

Does the guidance cost anything?

No. The personal guidance is free and confidential.

Who reviews the findings?

Oncologist Jason Sager, MD and the Sagely Health team review the findings before they are sent to you.

Find cancer clinical trials matched to your diagnosis.

Sagely's clinical trial matching service looks beyond long trial lists. Tell us about your situation and receive free, personal guidance on relevant trials, the science behind them, tests that may clarify fit, and doctors or cancer centers worth discussing.

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Free · Confidential · Reviewed by an oncologist

See an example response

How our clinical trial matching service prioritizes results.

A useful match is more than an eligibility check. We consider whether the science is relevant to patients like you, what information is still needed, and where the right expertise may be available.

Your diagnosis, stage, and treatment history

We start with the details that determine whether a study may be relevant and whether its approach fits where you are in treatment.

Biomarkers and diagnostic questions

A promising option may depend on testing you have already completed—or a diagnostic worth asking your care team about.

The strength and relevance of the science

We look at what the treatment is designed to do and how closely the available evidence relates to patients with situations like yours.

Doctors and cancer centers connected to the work

Sometimes the most useful next step is identifying an expert or center with experience in the disease, treatment approach, or relevant studies.

How Sagely helps

See how Sagely helps patients explore clinical trials.

Dr. Jason Sager explains how a focused search can bring together trial options, the science behind them, and the experts or cancer centers connected to the work.

Personal guidance for deciding what to explore next.

Instead of sending you a database, Sagely prioritizes a small set of findings, explains why each may matter, and gives you useful ways to continue the conversation with your care team or a trial site. Dr. Jason Sager and the Sagely team review the guidance.

See an example response

Your personal response

Oncologist-reviewed

Relevant trial options

Studies that appear to fit your diagnosis, stage, prior treatments, biomarkers, location, and other known details.

Why each option may matter

Plain-English context on what is being tested, who the study is designed for, and questions worth discussing.

Experts, centers, and ways to connect

Official study links and contacts, doctors involved in relevant work, and cancer centers you may want to reach out to. Trial teams make the final eligibility and enrollment decisions.

An example response from Dr. Sager

Illustrative example. Guidance is personalized to each person’s diagnosis, treatment history, and questions.

Subject: Follow-up from Dr. Sager at Sagely Health

Dear Sarah,

Thank you for reaching out and sharing what has been happening. I’m sorry your latest scan showed that the pancreatic cancer is growing despite chemotherapy. I’m glad you contacted us as you consider what comes next.

One detail in your tumor testing provides a clue for personalized cancer treatment: a gene change called KRAS G12D. Instead of only looking for generic (or unselected) pancreatic cancer trials, we can look for studies testing treatments specifically designed for this change. There are more than 30 KRAS drugs being tested with about half already showing promising data, and 2 that have already been FDA-approved.

One study worth discussing evaluates RMC-9805, a pill designed to block the altered KRAS G12D protein. It includes people with advanced pancreatic cancer with this mutation who have already received standard treatment. This is an early study, and initial results have been reported, but it is not yet clear whether RMC-9805 would help in your case. However, because it is specific for the G12D mutation, we believe it could be better than a medicine that covers all KRAS mutations or cause fewer side effects like rash.

Since you live near Baltimore, Johns Hopkins is a nearby center to ask about this trial. Dr. Nilo Azad is on Johns Hopkins' early-phase trials team, though the study listing does not confirm that she leads it locally. You can reach the program's referral nurse at 410-502-5140 and ask about the RMC-9805 study.

Your mutation alone does not establish eligibility—the team would need to review your treatment history and overall health. They would also need to confirm whether a slot is available. When you see them to learn more about the trial, ask how often you would need to visit so you can consider the practical side, too.

Your oncologist likely has standard treatment options; a second opinion with Dr. Azad could help you compare those with trial options, such as the RMC-9805 study.

When is your next oncology appointment? Please let me know, along with any questions or concerns you would like help working through, especially if you have trouble reaching Dr. Azad

Best wishes,

Jason Sager, MD
Founder, Sagely Health

Have questions about your own options?

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The oncologist writing your response

Guidance from people who have spent their careers inside cancer care.

Sagely Health was founded by Jason Sager, MD — an oncologist, biotech drug developer, and researcher — after seeing how often the right information could change everything for a patient. Since 2014, our team and technology have helped hundreds of patients and families move forward with clarity.

“I built Sagely Health to make sure patients don’t have to face those moments alone.”— Jason Sager, MD, Founder

Jason Sager, MDFounder

Pediatric oncologist who has treated cancer patients directly
Biotech leader who has developed new cancer therapies
Researcher focused on what actually improves outcomes
Tracks tens of thousands of treatments, trials, and oncologists

Since 2014

Helping cancer patients find better options — faster.

From patients and families

The right trial or expert can change the path forward.

“If I hadn't hired Sagely Health, my father would not have been enrolled in an immunotherapy trial that has multiplied his chances of survival.”

Caitlin M.

“The team immediately made me feel that 'I am not alone.' They were a steady hand, and referred me to three centers — two running trials relevant to my case.”

Noam L.

Before you begin

Questions about starting a trial search.

What does a cancer clinical trial matching service do?: A matching service compares the details of your situation—such as diagnosis, stage, prior treatments, biomarkers, and location—with study criteria and scientific context. Sagely then prioritizes a small set of findings and explains why each may be worth discussing. The trial team makes the final eligibility decision.
Is this only about clinical trials?: No. Trial matching can point toward diagnostics, doctors involved in relevant studies, cancer centers with useful expertise, and other treatment questions worth discussing.
How does Sagely help me connect with a trial or expert?: When Sagely identifies a relevant study or expert, your guidance can include official study links and contacts, doctors involved in the work, and cancer centers to reach out to. You decide which options to explore. The trial team reviews your records and makes the final eligibility and enrollment decision.
What information do I need?: Start with what you know. Sage asks guided questions, and you can upload records you already have. Your diagnosis, stage, prior treatments, biomarkers, and test results can all help make the guidance more useful.
Does the guidance cost anything?: No. The personal guidance is free and confidential.
Who reviews the findings?: Oncologist Jason Sager, MD and the Sagely Health team review the findings before they are sent to you.

You don’t have to navigate cancer alone.

Get free, confidential guidance about treatments, specialists, and questions that may matter for your situation — written by an oncologist.

Get free guidance

Free · Confidential · Built by cancer experts