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New trial
Prostate cancer

Phase Ib Elekta UNITY MR-Linac salvage SBRT + short ADT after prior EBRT

Trial ID
NCT07142967 on ClinicalTrials.gov
Cancer type
Prostate Cancer
Stage of research
Exploratory
Location
New York, NY
Published in
New in Oncology - Sept 12, 2025

NYU Langone trials MR-guided SBRT with online adaptive replanning plus 4–6 months of ADT in biopsy-proven local recurrence post-EBRT. Salvage options (surgery/cryo/HDR/SBRT) can control disease but GU toxicity is a key limiter; Elekta’s MR-Linac aims to tighten margins in real time (prostate motion, OAR sparing) to preserve urinary/sexual function. Endpoints include grade ≥2 GU/GI toxicity and biochemical control, positioning this beside or ahead of conventional salvage techniques.

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