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Sarcoma and GIST

Phase 1 MBRT: tungsten‐slit collimator enables spatially fractionated minibeam radiation therapy

Trial ID
NCT07062003 on ClinicalTrials.gov
Cancer type
Sarcoma (USTS)
Stage of research
First-in-human
Published in
New in Oncology - Aug 1, 2025

Investigating the safety and optimal dose of MBRT at Mayo Clinic, this study tests minibeam radiation—delivered via a tungsten slit collimator that creates alternating peak and valley dose regions—in patients with recurrent or metastatic skin and superficial soft tissue tumors using CT simulation and biospecimen collection.

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