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Breast cancer

Phase II Ivonescimab, a PD-1/VEGF bispecific antibody trial

Trial ID
NCT07017673 on ClinicalTrials.gov
Cancer type
Breast Cancer
Stage of research
Exploratory
Location
3 Locations
Published in
New in Oncology - July 3, 2025

This single arm study evaluates ivonescimab added to carboplatin and docetaxel administered every 3 weeks for 6 cycles as neoadjuvant therapy in early-stage triple negative breast cancer. Sponsored by Cedars-Sinai Medical Center, it assesses safety, pathological responses at surgery, and long-term outcomes with integrated imaging and biomarker analyses.

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