New trial
Phase 2 Trial: Ultra-Hypofractionated Whole Breast Irradiation With Concomitant Lumpectomy Cavity Boost
- Trial ID
- NCT06954831 on ClinicalTrials.gov
- Cancer type
- Breast Cancer
- Location
- 6 Locations
- Published in
- New in Oncology - May 14, 2025
City of Hope Medical Center is evaluating a five-fraction regimen that delivers both whole breast and lumpectomy cavity radiation over consecutive business days, aiming to reduce treatment time while maintaining efficacy in stage I–III breast cancer patients.
More in breast cancer
-
Trial result · Oct 22, 2026 · NCT02364557
NRG-BR002: Metastasis-directed ablation (SBRT/surgery) fails to extend PFS in oligometastatic breast cancer on 1L systemic therapy -
Trial result · Oct 22, 2026 · NCT05963984
Samuraciclib + fulvestrant shows higher clinical benefit and numerically longer PFS after CDK4/6 inhibition in randomized Phase 2 breast cancer trial -
Trial result · Oct 15, 2026 · NCT05306340
Giredestrant (oral SERD) + everolimus improves PFS after CDK4/6 inhibition, with the strongest benefit in ESR1-mutated breast cancer -
Trial result · Oct 15, 2026 · NCT02264678
Ceralasertib (ATR inhibitor) + Olaparib (PARP inhibitor) hits 37.8% ORR in PARPi‑naïve BRCA‑mut HER2‑neg breast cancer -
New trial · Oct 15, 2026 · NCT07844759
Pilot study tests single-fraction stereotactic radiation plus endocrine therapy without lumpectomy in early breast cancer
