New trial
Phase 1b/2a Study Evaluates SNIPR001 with Levofloxacin in HSCT Patients Harboring FQR E. coli
- Trial ID
- NCT06938867 on ClinicalTrials.gov
- Cancer type
- Hematological Cancers
- Published in
- New in Oncology - May 7, 2025
SNIPR Biome Aps. is investigating the safety, PK/PD, and preliminary efficacy of SNIPR001 administered with standard levofloxacin in allogeneic HSCT recipients colonized with fluoroquinolone-resistant E. coli. This randomized, double-blind trial in New York aims to assess whether SNIPR001 can enhance outcomes in hematologic malignancy patients facing antibiotic-resistant infections pre-transplant.
More in other blood cancers and transplant
-
Trial result · Aug 13, 2026 · NCT04904588
Standard-dose PTCy enables mismatched-donor HCT but carries substantial early infection burden -
Trial result · Aug 6, 2026 · NCT05388123
Low-dose vemurafenib (BRAF V600E inhibitor) + rituximab drives 73% CR with zero grade 3-4 AEs in HCL -
Trial result · Aug 6, 2026 · NCT02113982
Tagraxofusp (CD123-directed cytotoxin) in BPDCN delivers 71%–90% ORR across trials—HSCT bridge drives survival -
New trial · Jun 25, 2026 · NCT07634536
Phase 2 automated VMAT-based TMLI conditioning refines marrow / lymphoid-targeted irradiation for allo-HCT. -
New trial · Jun 25, 2026 · NCT07572006
Phase 1 JNJ-95804306 (no disclosed MOA/target) in relapsed/refractory AML/MDS and CLL/SLL
