New trial
Phase 2 Study: ctDNA-Guided Neoadjuvant and Adjuvant Pembrolizumab in Early-Stage NSCLC
- Trial ID
- NCT06902272 on ClinicalTrials.gov
- Cancer type
- Non-Small Cell Lung Cancer
- Published in
- New in Oncology - May 14, 2025
University of Miami is evaluating whether circulating tumor DNA (ctDNA) can predict response to neoadjuvant platinum-based chemotherapy and surgery, and guide adjuvant pembrolizumab treatment to prevent cancer recurrence.
More in non-small cell lung cancer
-
Trial result · Oct 22, 2026 · NCT04905316
Canakinumab (IL-1β blockade) + cCRT and durvalumab consolidation hits 67% 24-mo PFS in unresectable stage III NSCLC -
Trial result · Oct 15, 2026 · NCT04495153
CAN-2409 + valacyclovir reports 14.3-month median OS in treated NSCLC patients; 24.5 months in a selected per-protocol group -
New trial · Oct 15, 2026 · NCT07852247
Phase 1 CyberKnife SBRT uses Synchrony respiratory motion tracking for ultra-central NSCLC -
New trial · Oct 15, 2026 · NCT07617337
Phase 1 AQUA07 allosteric ALK inhibitor (macrocyclic peptide) alone or with lorlatinib in ALK-positive NSCLC -
Trial result · Oct 8, 2026 · NCT03052608
AI volumetric brain-met response may better predict PFS in ALK+ NSCLC