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Pancreatic cancer

A Pilot Study Comparing Neoadjuvant and Adjuvant GVAX vs a Mutated KRAS Peptide Vaccine Given With Anti-PD-1 and Anti-CD137 for the Treatment of Surgically Resectable Pancreatic Adenocarcinoma

Trial ID
NCT06782932 on ClinicalTrials.gov
Cancer type
Pancreatic Ductal Adenocarcinoma (PDAC)
Published in
New in Oncology - May 21, 2025

Johns Hopkins is investigating the optimal dosing and safety of AGEN2373 combined with balstilimab alongside either GVAX or a mutated KRAS peptide vaccine, aimed at enhancing neoadjuvant and adjuvant treatment efficacy in newly diagnosed resectable pancreatic adenocarcinoma.

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