New trial
Phase 2 Tarlatamab Trial: DLL3 and CD3-directed bispecific antibody
- Trial ID
- NCT06745323 on ClinicalTrials.gov
- Cancer type
- SCLC
- Location
- 34 Locations
- Published in
- New in Oncology - June 16, 2025
This open-label randomized study evaluates Tarlatamab dosing regimens in patients with relapsed or refractory small cell lung cancer. Conducted at global centers by Amgen, it examines the antitumor activity of this novel bispecific antibody targeting DLL3 and CD3.
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Trial result · Aug 13, 2026
LIPI strongly stratifies survival in ES-SCLC but does not predict chemo-IO benefit
