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New trial
Sarcoma and GIST

Phase 1a/1b Study Combines Menin Inhibition with Imatinib in Advanced GIST

Trial ID
NCT06655246 on ClinicalTrials.gov
Cancer type
Gastrointestinal Stromal Tumor (GIST)
Location
2 Locations
Published in
New in Oncology - May 7, 2025

Kura Oncology is assessing the safety, tolerability, and initial efficacy of oral ziftomenib combined with imatinib in adults with advanced, KIT-mutant gastrointestinal stromal tumors post-imatinib failure. This study, with dose escalation and expansion arms, aims to define the optimal regimen across sites in New York and Houston.

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