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New trial
Liver and bile duct cancer

Phase I/II trial of Pemigatinib FGFR1-3 inhibitor in advanced cholangiocarcinoma

Trial ID
NCT06439485 on ClinicalTrials.gov
Cancer type
Cholangiocarcinoma
Stage of research
Exploratory
Published in
New in Oncology - June 27, 2025

This study, sponsored by M.D. Anderson Cancer Center, evaluates pemigatinib combined with atezolizumab and bevacizumab in patients with unresectable, advanced cholangiocarcinoma harboring FGFR2 fusion. The trial features a dose-escalation phase followed by expansion at the recommended dose to assess safety and preliminary efficacy.

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